Drug General Information
Drug ID
DX2KJK
Drug Name
2-[(R)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]-isoindole-1,3-dione
Synonyms
CHEMBL100738
Indication Discovery agent Investigative [1587926]
Formula
C33H28ClN5O3
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)[C@@H](Cc4c[nH]cn4)N5C(=O)c6ccccc6C5=O)c7ncccc7CCc2c1
InChI
InChI=1S/C33H28ClN5O3/c34-23-9-10-25-22(16-23)8-7-21-4-3-13-36-30(21)29(25)20-11-14-38(15-12-20)33(42)28(17-24-18-35-19-37-24)39-31(40)26-5-1-2-6-27(26)32(39)41/h1-6,9-10,13,16,18-19,28H,7-8,11-12,14-15,17H2,(H,35,37)/t28-/m1/s1
InChIKey
DYOAIRZCSZTXNA-MUUNZHRXSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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