Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2RXE
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| Drug Name |
N-((S)-1-(1-(5-fluoroindolin-1-yl)-4-(methylsulfonyl)butan-2-ylamino)-4,4-dimethyl-1-oxopentan-2-yl)-3-methoxybenzamide
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| Synonyms |
CHEMBL202747
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H38FN3O5S
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| Canonical SMILES |
COc1cccc(c1)C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](CCS(=O)(=O)C)CN2CCc3cc(F)ccc23
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| InChI |
InChI=1S/C28H38FN3O5S/c1-28(2,3)17-24(31-26(33)20-7-6-8-23(16-20)37-4)27(34)30-22(12-14-38(5,35)36)18-32-13-11-19-15-21(29)9-10-25(19)32/h6-10,15-16,22,24H,11-14,17-18H2,1-5H3,(H,30,34)(H,31,33)/t22-,24-/m0/s1
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| InChIKey |
CFYHMIZKUOLIBJ-UPVQGACJSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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