Drug Information
| Drug General Information | |||||
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| Drug ID |
DX2STI
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| Drug Name |
N-((S)-1-((2R,3R)-3-(benzyloxy)-1-(5-fluoroindolin-1-yl)butan-2-ylamino)-4-cyclohexyl-1-oxobutan-2-yl)-3-methoxybenzamide
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| Synonyms |
CHEMBL206057
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C37H46FN3O4
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| Canonical SMILES |
COc1cccc(c1)C(=O)N[C@@H](CCC2CCCCC2)C(=O)N[C@H](CN3CCc4cc(F)ccc34)[C@@H](C)OCc5ccccc5
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| InChI |
InChI=1S/C37H46FN3O4/c1-26(45-25-28-12-7-4-8-13-28)34(24-41-21-20-29-22-31(38)17-19-35(29)41)40-37(43)33(18-16-27-10-5-3-6-11-27)39-36(42)30-14-9-15-32(23-30)44-2/h4,7-9,12-15,17,19,22-23,26-27,33-34H,3,5-6,10-11,16,18,20-21,24-25H2,1-2H3,(H,39,42)(H,40,43)/t26-,33+,34-/m1/s1
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| InChIKey |
CXYMWYIUDRQGTR-VCXVHRGASA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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