Drug Information

Drug General Information
Drug ID
DX3GBL
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid pyridin-3-ylamide
Synonyms
CHEMBL201044
Indication Discovery agent Investigative [1587926]
Formula
C29H31BrClN5O2
Canonical SMILES
CCCCC(=O)N1CCN(CC1C(=O)Nc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C29H31BrClN5O2/c1-2-3-6-26(37)36-13-12-35(18-25(36)29(38)34-23-5-4-11-32-17-23)28-24-10-9-22(31)15-19(24)7-8-20-14-21(30)16-33-27(20)28/h4-5,9-11,14-17,25,28H,2-3,6-8,12-13,18H2,1H3,(H,34,38)
InChIKey
DHAAFTKZGRVWHT-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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