Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3LNX
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| Drug Name |
9-(3-hydroxy-propyl)-6-(4-methyl-benzylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL255087
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C17H18N6O
|
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| Canonical SMILES |
Cc1ccc(CNc2nc(nc3c2ncn3CCCO)C#N)cc1
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| InChI |
InChI=1S/C17H18N6O/c1-12-3-5-13(6-4-12)10-19-16-15-17(22-14(9-18)21-16)23(11-20-15)7-2-8-24/h3-6,11,24H,2,7-8,10H2,1H3,(H,19,21,22)
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| InChIKey |
DBHAVZJJDUOEBA-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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