Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3LRM
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| Drug Name |
N-{(S)-2-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-4-piperazin-1-yl-benzamide
|
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| Synonyms |
CHEMBL198494
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H40N4O4
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3ccc(cc3)N4CCOCC4)cc1
|
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| InChI |
InChI=1S/C29H40N4O4/c1-36-26-13-9-24(10-14-26)30-15-16-31-29(35)27(21-22-5-3-2-4-6-22)32-28(34)23-7-11-25(12-8-23)33-17-19-37-20-18-33/h7-14,22,27,30H,2-6,15-21H2,1H3,(H,31,35)(H,32,34)/t27-/m0/s1
|
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| InChIKey |
ZUPMPYFEIHADDD-MHZLTWQESA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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