Drug Information

Drug General Information
Drug ID
DX3MCQ
Drug Name
(R)-5-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-5-oxo-pentanoic acid phenylamide
Synonyms
CHEMBL327507
Indication Discovery agent Investigative [1587926]
Formula
C38H33ClN4O4
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)[C@@H](CCC(=O)Nc4ccccc4)N5C(=O)c6ccccc6C5=O)c7ncccc7CCc2c1
InChI
InChI=1S/C38H33ClN4O4/c39-27-14-15-29-26(23-27)13-12-25-7-6-20-40-35(25)34(29)24-18-21-42(22-19-24)38(47)32(16-17-33(44)41-28-8-2-1-3-9-28)43-36(45)30-10-4-5-11-31(30)37(43)46/h1-11,14-15,20,23,32H,12-13,16-19,21-22H2,(H,41,44)/t32-/m1/s1
InChIKey
QCTBCNADSCKGSK-JGCGQSQUSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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