Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3PBS
|
||||
| Drug Name |
3-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid
|
||||
| Synonyms |
CHEMBL334717
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H27N3O4
|
||||
| Canonical SMILES |
Cc1cccc(C[C@H](Nc2ccccc2)C(=O)N[C@@H](COCc3cccc(c3)C(=O)O)C#N)c1
|
||||
| InChI |
InChI=1S/C27H27N3O4/c1-19-7-5-8-20(13-19)15-25(29-23-11-3-2-4-12-23)26(31)30-24(16-28)18-34-17-21-9-6-10-22(14-21)27(32)33/h2-14,24-25,29H,15,17-18H2,1H3,(H,30,31)(H,32,33)/t24-,25+/m1/s1
|
||||
| InChIKey |
IJAQOHJCVHKRNN-RPBOFIJWSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.