Drug Information

Drug General Information
Drug ID
DX3PVO
Drug Name
(R)-4-Dicyclohexylcarbamoyl-4-[(1H-indole-2-carbonyl)-amino]-butyric acid
Synonyms
CHEMBL422873
Indication Discovery agent Investigative [1587926]
Formula
C26H35N3O4
Canonical SMILES
OC(=O)CC[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N(C3CCCCC3)C4CCCCC4
InChI
InChI=1S/C26H35N3O4/c30-24(31)16-15-22(28-25(32)23-17-18-9-7-8-14-21(18)27-23)26(33)29(19-10-3-1-4-11-19)20-12-5-2-6-13-20/h7-9,14,17,19-20,22,27H,1-6,10-13,15-16H2,(H,28,32)(H,30,31)/t22-/m0/s1
InChIKey
OKFKXUMMUSRABT-QFIPXVFZSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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