Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4LOB
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(morpholinomethyl)thiazol-4-yl)benzamide
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| Synonyms |
CHEMBL381026
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H29N5O3S
|
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| Canonical SMILES |
O=C(NC1(CCCCC1)C(=O)NCC#N)c2ccc(cc2)c3csc(CN4CCOCC4)n3
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| InChI |
InChI=1S/C24H29N5O3S/c25-10-11-26-23(31)24(8-2-1-3-9-24)28-22(30)19-6-4-18(5-7-19)20-17-33-21(27-20)16-29-12-14-32-15-13-29/h4-7,17H,1-3,8-9,11-16H2,(H,26,31)(H,28,30)
|
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| InChIKey |
DSANAVRTRJWZMT-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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