Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5EBI
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| Drug Name |
5-(3-(4-(4-methylpiperazin-1-yl)phenyl)prop-1-ynyl)-4-(neopentylamino)pyrimidine-2-carbonitrile
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| Synonyms |
CHEMBL259939
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H30N6
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(CC#Cc3cnc(nc3NCC(C)(C)C)C#N)cc2
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| InChI |
InChI=1S/C24H30N6/c1-24(2,3)18-27-23-20(17-26-22(16-25)28-23)7-5-6-19-8-10-21(11-9-19)30-14-12-29(4)13-15-30/h8-11,17H,6,12-15,18H2,1-4H3,(H,26,27,28)
|
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| InChIKey |
RVYUARIENPNTJS-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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