Drug General Information
Drug ID
DX5FFE
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[3-(3H-imidazol-4-yl)-propyl]-amide}
Synonyms
CHEMBL201903
Indication Discovery agent Investigative [1587926]
Formula
C32H39BrClN7O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCc4c[nH]cn4)C(=O)NC5CCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C32H39BrClN7O2/c33-23-15-22-9-8-21-16-24(34)10-11-27(21)30(29(22)37-17-23)40-13-14-41(32(43)39-25-5-2-1-3-6-25)28(19-40)31(42)36-12-4-7-26-18-35-20-38-26/h10-11,15-18,20,25,28,30H,1-9,12-14,19H2,(H,35,38)(H,36,42)(H,39,43)
InChIKey
DKBCPWSPMZLASX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Wang and Dr. Li.