Drug Information

Drug General Information
Drug ID
DX5GGL
Drug Name
(2R,3S)-3-(2-Hydroxy-4-iodo-benzoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Synonyms
CHEMBL311144
Indication Discovery agent Investigative [1587926]
Formula
C17H20INO5
Canonical SMILES
COC(=O)[C@H]1[C@H](CC2CCC1N2C)OC(=O)c3ccc(I)cc3O
InChI
InChI=1S/C17H20INO5/c1-19-10-4-6-12(19)15(17(22)23-2)14(8-10)24-16(21)11-5-3-9(18)7-13(11)20/h3,5,7,10,12,14-15,20H,4,6,8H2,1-2H3/t10?,12?,14-,15+/m0/s1
InChIKey
QYYWMLHRGDGTBW-TVSZOZCSSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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