Drug Information

Drug General Information
Drug ID
DX6BV5
Drug Name
2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(2-(4-chlorophenyl)-2-methylpropyl)benzamide
Synonyms
CHEMBL565511
Indication Discovery agent Investigative [1587926]
Formula
C23H20Cl2N4O3S2
Canonical SMILES
CC(C)(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2cccc3nsnc23)c4ccc(Cl)cc4
InChI
InChI=1S/C23H20Cl2N4O3S2/c1-23(2,14-6-8-15(24)9-7-14)13-26-22(30)17-11-10-16(25)12-19(17)29-34(31,32)20-5-3-4-18-21(20)28-33-27-18/h3-12,29H,13H2,1-2H3,(H,26,30)
InChIKey
GEKZDEGHQMAZQZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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