Drug General Information
Drug ID
DX6K1S
Drug Name
2-((3,5-dichlorophenyl)(thiophen-2-yl)methylene)hydrazinecarbothioamide
Synonyms
CHEMBL496424
Indication Discovery agent Investigative [1587926]
Formula
C12H9Cl2N3S2
Canonical SMILES
NC(=S)N\\N=C(/c1cc(Cl)cc(Cl)c1)\\c2cccs2
InChI
InChI=1S/C12H9Cl2N3S2/c13-8-4-7(5-9(14)6-8)11(16-17-12(15)18)10-2-1-3-19-10/h1-6H,(H3,15,17,18)/b16-11+
InChIKey
GLGCLPLEIOLAJV-LFIBNONCSA-N
Target and Pathway
Target(s) Cathepsin L Target Info [1587926]
Cathepsin B Target Info [1587926]
KEGG Pathway Lysosome
Phagosome
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritishsa04142:Lysosome
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling PathwayNetPath_11:TCR Signaling Pathway
IL2 Signaling Pathway
Reactome Endosomal/Vacuolar pathway
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentationR-HSA-1442490:Collagen degradation
MHC class II antigen presentation
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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