Drug Information

Drug General Information
Drug ID
DX6KM8
Drug Name
1-[4-(2-Bromo-8-chloro-11H-10-oxa-4-aza-dibenzo[a,d]cyclohepten-5-ylidene)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL85141
Indication Discovery agent Investigative [1587926]
Formula
C25H21BrClN3O3
Canonical SMILES
[O-][n+]1ccc(CC(=O)N2CCC(=C3c4ccc(Cl)cc4OCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C25H21BrClN3O3/c26-19-12-18-15-33-22-13-20(27)1-2-21(22)24(25(18)28-14-19)17-5-7-29(8-6-17)23(31)11-16-3-9-30(32)10-4-16/h1-4,9-10,12-14H,5-8,11,15H2
InChIKey
ZRMWHAYAESKTOA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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