Drug General Information
Drug ID
DX6KRU
Drug Name
3-(4-(4-methoxyphenyl)piperazin-1-yl)-1-phenylpropan-1-ol
Synonyms
CHEMBL444335
Indication Discovery agent Investigative [1587926]
Formula
C20H26N2O2
Canonical SMILES
COc1ccc(cc1)N2CCN(CCC(O)c3ccccc3)CC2
InChI
InChI=1S/C20H26N2O2/c1-24-19-9-7-18(8-10-19)22-15-13-21(14-16-22)12-11-20(23)17-5-3-2-4-6-17/h2-10,20,23H,11-16H2,1H3
InChIKey
XJDBPHRIKPQDFL-UHFFFAOYSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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