Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6UCP
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| Drug Name |
2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[3-(4-methyl-piperazin-1-yl)-phenyl]-ethyl}-amide
|
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| Synonyms |
CHEMBL414530
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H33N7O
|
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| Canonical SMILES |
CN1CCN(CC1)c2cccc(CCNC(=O)c3cnc(nc3NCC(C)(C)C)C#N)c2
|
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| InChI |
InChI=1S/C24H33N7O/c1-24(2,3)17-28-22-20(16-27-21(15-25)29-22)23(32)26-9-8-18-6-5-7-19(14-18)31-12-10-30(4)11-13-31/h5-7,14,16H,8-13,17H2,1-4H3,(H,26,32)(H,27,28,29)
|
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| InChIKey |
LCGRTAPRJZMTIT-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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