Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6YMB
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| Drug Name |
6-Cyclohexylamino-9-((2R,3R,4S,5S)-3,4,5-trihydroxy-tetrahydro-furan-2-yl)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL365564
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H20N6O4
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| Canonical SMILES |
O[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCCC4)nc(nc23)C#N
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| InChI |
InChI=1S/C16H20N6O4/c17-6-9-20-13(19-8-4-2-1-3-5-8)10-14(21-9)22(7-18-10)15-11(23)12(24)16(25)26-15/h7-8,11-12,15-16,23-25H,1-5H2,(H,19,20,21)/t11-,12+,15-,16+/m1/s1
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| InChIKey |
OKAYCQSOIKKHMZ-KOZAUXTDSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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