Drug Information

Drug General Information
Drug ID
DX6YXM
Drug Name
4-(3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one
Synonyms
CHEMBL210578
Indication Discovery agent Investigative [1587926]
Formula
C23H25ClFNO2
Canonical SMILES
OC1(CC2CCC(C1)N2CCCC(=O)c3ccc(F)cc3)c4ccc(Cl)cc4
InChI
InChI=1S/C23H25ClFNO2/c24-18-7-5-17(6-8-18)23(28)14-20-11-12-21(15-23)26(20)13-1-2-22(27)16-3-9-19(25)10-4-16/h3-10,20-21,28H,1-2,11-15H2
InChIKey
CXQUOFVDYCOSEZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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