Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7GEJ
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| Drug Name |
{3-Methyl-1-[2-oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-butyl}-carbamic acid pyridin-3-ylmethyl ester
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| Synonyms |
CHEMBL321974
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H41N3O4S
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1cccnc1)C(=O)N[C@@H](CCc2ccccc2)C(=O)CSCCCc3ccccc3
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| InChI |
InChI=1S/C33H41N3O4S/c1-25(2)21-30(36-33(39)40-23-28-15-9-19-34-22-28)32(38)35-29(18-17-27-13-7-4-8-14-27)31(37)24-41-20-10-16-26-11-5-3-6-12-26/h3-9,11-15,19,22,25,29-30H,10,16-18,20-21,23-24H2,1-2H3,(H,35,38)(H,36,39)/t29-,30-/m0/s1
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| InChIKey |
ZFHURWWCUFDMNR-KYJUHHDHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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