Drug General Information
Drug ID
DX7J6L
Drug Name
{[2-(Adamantan-2-yloxycarbonylamino)-2-methyl-3-naphthalen-1-yl-propionyl]-phenethyl-amino}-acetic acid
Synonyms
CHEMBL98516
Indication Discovery agent Investigative [1587926]
Formula
C35H40N2O5
Canonical SMILES
CC(Cc1cccc2ccccc12)(NC(=O)OC3[C@@H]4C[C@H]5C[C@H](C[C@@H]3C5)C4)C(=O)N(CCc6ccccc6)CC(=O)O
InChI
InChI=1S/C35H40N2O5/c1-35(21-27-12-7-11-26-10-5-6-13-30(26)27,33(40)37(22-31(38)39)15-14-23-8-3-2-4-9-23)36-34(41)42-32-28-17-24-16-25(19-28)20-29(32)18-24/h2-13,24-25,28-29,32H,14-22H2,1H3,(H,36,41)(H,38,39)/t24-,25+,28-,29+,32?,35?
InChIKey
DDMOESJKCONAST-CRYGHHFHSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.