Drug General Information
Drug ID
DX7K9I
Drug Name
4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonitrile
Synonyms
CHEMBL507671
Indication Discovery agent Investigative [1587926]
Formula
C14H7F4NS
Canonical SMILES
Fc1ccccc1Sc2ccc(C#N)c(c2)C(F)(F)F
InChI
InChI=1S/C14H7F4NS/c15-12-3-1-2-4-13(12)20-10-6-5-9(8-19)11(7-10)14(16,17)18/h1-7H
InChIKey
OZEYWYWKQCOUOK-UHFFFAOYSA-N
Target and Pathway
Target(s) Progesterone receptor Target Info [1587926]
mRNA of androgen receptor Target Info [1587926]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturationhsa04114:Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Cellular roles of Anthrax toxinsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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