Drug General Information
Drug ID
DX7NHC
Drug Name
(+)1-[4-(10-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL340432
Indication Discovery agent Investigative [1587926]
Formula
C26H25BrClN3O2
Canonical SMILES
[O-][n+]1ccc(CC(=O)N2CCC(CC2)[C@H]3c4ncccc4CCc5cc(Cl)cc(Br)c35)cc1
InChI
InChI=1S/C26H25BrClN3O2/c27-22-16-21(28)15-20-4-3-19-2-1-9-29-26(19)25(24(20)22)18-7-10-30(11-8-18)23(32)14-17-5-12-31(33)13-6-17/h1-2,5-6,9,12-13,15-16,18,25H,3-4,7-8,10-11,14H2/t25-/m1/s1
InChIKey
PPXJVZJWVHFFJW-RUZDIDTESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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