Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7PU3
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| Drug Name |
1H-Indole-2-carboxylic acid {(S)-1-[2-(4-cyclohexylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide
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| Synonyms |
CHEMBL60835
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H34N4O3
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)NCCNc3ccc(OCc4ccccc4)cc3
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| InChI |
InChI=1S/C30H34N4O3/c1-21(2)18-27(34-30(36)28-19-23-10-6-7-11-26(23)33-28)29(35)32-17-16-31-24-12-14-25(15-13-24)37-20-22-8-4-3-5-9-22/h3-15,19,21,27,31,33H,16-18,20H2,1-2H3,(H,32,35)(H,34,36)/t27-/m0/s1
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| InChIKey |
KALFEJDRRGDYIW-MHZLTWQESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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