Drug General Information
Drug ID
DX7SMG
Drug Name
2-mercaptopyridine 1-oxide
Synonyms
Pyrithione; CHEMBL1356238
Indication Discovery agent Investigative [1587926]
Formula
C5H5NOS
Canonical SMILES
[O-][n+]1ccccc1S
InChI
InChI=1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,8H
InChIKey
FGVVTMRZYROCTH-UHFFFAOYSA-N
Target and Pathway
Target(s) Carbonic anhydrase IX Target Info [1587926]
Carbonic anhydrase XII Target Info [1587926]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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