Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8XUU
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| Drug Name |
9-Cyclopentyl-6-{2-[3-(4-methyl-piperazin-1-yl)-propoxy]-phenylamino}-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL188139
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H32N8O
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| Canonical SMILES |
CN1CCN(CCCOc2ccccc2Nc3nc(nc4c3ncn4C5CCCC5)C#N)CC1
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| InChI |
InChI=1S/C25H32N8O/c1-31-12-14-32(15-13-31)11-6-16-34-21-10-5-4-9-20(21)28-24-23-25(30-22(17-26)29-24)33(18-27-23)19-7-2-3-8-19/h4-5,9-10,18-19H,2-3,6-8,11-16H2,1H3,(H,28,29,30)
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| InChIKey |
VWGLHPDSAYQVRM-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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