Drug Information
| Drug General Information | |||||
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| Drug ID |
DX9AML
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| Drug Name |
(S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(5-fluoro-3,3-dimethylindolin-1-yl)propan-2-yl)propanamide
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| Synonyms |
CHEMBL381186
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H36ClFN4O2
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| Canonical SMILES |
C[C@@H](CN1CC(C)(C)c2cc(F)ccc12)NC(=O)[C@H](CC3CCCCC3)Nc4oc5c(Cl)cccc5n4
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| InChI |
InChI=1S/C29H36ClFN4O2/c1-18(16-35-17-29(2,3)21-15-20(31)12-13-25(21)35)32-27(36)24(14-19-8-5-4-6-9-19)34-28-33-23-11-7-10-22(30)26(23)37-28/h7,10-13,15,18-19,24H,4-6,8-9,14,16-17H2,1-3H3,(H,32,36)(H,33,34)/t18-,24-/m0/s1
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| InChIKey |
SHLWXCGNHANUPZ-UUOWRZLLSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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