Drug Information

Drug General Information
Drug ID
DX9BIL
Drug Name
2-(1-Acetyl-piperidin-4-yl)-1-[4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone
Synonyms
CHEMBL354747
Indication Discovery agent Investigative [1587926]
Formula
C27H32BrClN4O2
Canonical SMILES
CC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC1
InChI
InChI=1S/C27H32BrClN4O2/c1-18(34)31-8-6-19(7-9-31)14-25(35)32-10-12-33(13-11-32)27-24-5-4-23(29)16-20(24)2-3-21-15-22(28)17-30-26(21)27/h4-5,15-17,19,27H,2-3,6-14H2,1H3
InChIKey
SEHLSBMUTCCSCL-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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