Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9HWF
|
||||
| Drug Name |
2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid {2-[4-(4-methylpiperazin-1-yl)-phenyl]-ethyl}-amide
|
||||
| Synonyms |
CHEMBL219536
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H33N7O
|
||||
| Canonical SMILES |
CN1CCN(CC1)c2ccc(CCNC(=O)c3cnc(nc3NC4CCCCC4)C#N)cc2
|
||||
| InChI |
InChI=1S/C25H33N7O/c1-31-13-15-32(16-14-31)21-9-7-19(8-10-21)11-12-27-25(33)22-18-28-23(17-26)30-24(22)29-20-5-3-2-4-6-20/h7-10,18,20H,2-6,11-16H2,1H3,(H,27,33)(H,28,29,30)
|
||||
| InChIKey |
DNXUCHBIMIYWNQ-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.