Drug Information

Drug General Information
Drug ID
DX9NGH
Drug Name
4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid methyl-pyridin-3-yl-amide
Synonyms
CHEMBL354071
Indication Discovery agent Investigative [1587926]
Formula
C25H26ClN5O
Canonical SMILES
CN(C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cccnc24)c5cccnc5
InChI
InChI=1S/C25H26ClN5O/c1-29(21-5-3-10-27-17-21)25(32)31-14-12-30(13-15-31)24-22-9-8-20(26)16-19(22)7-6-18-4-2-11-28-23(18)24/h2-5,8-11,16-17,24H,6-7,12-15H2,1H3
InChIKey
DIKKNRCBPSWRFQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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