Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9Y5B
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| Drug Name |
6-[4-(4-Acetyl-piperazin-1-yl)-2-fluoro-phenoxymethyl]-7-(2-cyclohexyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile
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| Synonyms |
CHEMBL494517
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H33FN6O2
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| Canonical SMILES |
CC(=O)N1CCN(CC1)c2ccc(OCc3cc4cnc(nc4n3CCC5CCCCC5)C#N)c(F)c2
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| InChI |
InChI=1S/C28H33FN6O2/c1-20(36)33-11-13-34(14-12-33)23-7-8-26(25(29)16-23)37-19-24-15-22-18-31-27(17-30)32-28(22)35(24)10-9-21-5-3-2-4-6-21/h7-8,15-16,18,21H,2-6,9-14,19H2,1H3
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| InChIKey |
RKKQUNNKTWJTLY-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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