Drug General Information
Drug ID
DXA0RK
Drug Name
1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-[1-(1-oxy-pyridine-4-carbonyl)-piperidin-4-yl]-ethanone
Synonyms
CHEMBL327548
Indication Discovery agent Investigative [1587926]
Formula
C32H33Br2ClN4O3
Canonical SMILES
[O-][n+]1ccc(cc1)C(=O)N2CCC(CC(=O)N3CCC(CC3)[C@H]4c5ncc(Br)cc5CCc6cc(Cl)cc(Br)c46)CC2
InChI
InChI=1S/C32H33Br2ClN4O3/c33-25-16-24-2-1-23-17-26(35)18-27(34)29(23)30(31(24)36-19-25)21-5-11-37(12-6-21)28(40)15-20-3-9-38(10-4-20)32(41)22-7-13-39(42)14-8-22/h7-8,13-14,16-21,30H,1-6,9-12,15H2/t30-/m1/s1
InChIKey
ZFBLLHIHVGCQFY-SSEXGKCCSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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