Drug Information

Drug General Information
Drug ID
DXA1TE
Drug Name
4-{2-[(S)-4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-butyl-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid amide
Synonyms
CHEMBL169867
Indication Discovery agent Investigative [1587926]
Formula
C30H39BrClN5O2
Canonical SMILES
CCCC[C@H]1CN(CCN1C(=O)CC2CCN(CC2)C(=O)N)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C30H39BrClN5O2/c1-2-3-4-25-19-36(13-14-37(25)27(38)15-20-9-11-35(12-10-20)30(33)39)29-26-8-7-24(32)17-21(26)5-6-22-16-23(31)18-34-28(22)29/h7-8,16-18,20,25,29H,2-6,9-15,19H2,1H3,(H2,33,39)/t25-,29?/m0/s1
InChIKey
FRZPVFJBZMEYQN-GMMLNUAGSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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