Drug General Information
Drug ID
DXA3E1
Drug Name
SID535898
Synonyms
CHEMBL609013
Indication Discovery agent Investigative [1587926]
Formula
C17H14N2O2
Canonical SMILES
Cc1cc2cc3OCOc3cc2c(n1)c4ccc(N)cc4
InChI
InChI=1S/C17H14N2O2/c1-10-6-12-7-15-16(21-9-20-15)8-14(12)17(19-10)11-2-4-13(18)5-3-11/h2-8H,9,18H2,1H3
InChIKey
ZHLRBDNNCVOICW-UHFFFAOYSA-N
Target and Pathway
Target(s) Cathepsin L Target Info [1587926]
Cathepsin B Target Info [1587926]
KEGG Pathway Lysosome
Phagosome
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritishsa04142:Lysosome
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling PathwayNetPath_11:TCR Signaling Pathway
IL2 Signaling Pathway
Reactome Endosomal/Vacuolar pathway
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentationR-HSA-1442490:Collagen degradation
MHC class II antigen presentation
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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