Drug Information

Drug General Information
Drug ID
DXA3QW
Drug Name
2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(2-pyridin-4-yl-acetyl)-piperazin-2-yl]-N-cyclopropyl-acetamide
Synonyms
CHEMBL200606
Indication Discovery agent Investigative [1587926]
Formula
C30H31BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(CC(=O)NC4CC4)C3)C(=O)Cc5ccncc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C30H31BrClN5O2/c31-22-14-21-2-1-20-15-23(32)3-6-26(20)30(29(21)34-17-22)36-11-12-37(28(39)13-19-7-9-33-10-8-19)25(18-36)16-27(38)35-24-4-5-24/h3,6-10,14-15,17,24-25,30H,1-2,4-5,11-13,16,18H2,(H,35,38)
InChIKey
JDIQHLJYMXXNKB-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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