Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXA5OU
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-(piperidin-1-yl)piperidin-1-yl)thiazol-4-yl)benzamide
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| Synonyms |
CHEMBL198798
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H38N6O2S
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| Canonical SMILES |
O=C(NC1(CCCCC1)C(=O)NCC#N)c2ccc(cc2)c3csc(n3)N4CCC(CC4)N5CCCCC5
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| InChI |
InChI=1S/C29H38N6O2S/c30-15-16-31-27(37)29(13-3-1-4-14-29)33-26(36)23-9-7-22(8-10-23)25-21-38-28(32-25)35-19-11-24(12-20-35)34-17-5-2-6-18-34/h7-10,21,24H,1-6,11-14,16-20H2,(H,31,37)(H,33,36)
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| InChIKey |
FSOSJHXWNDUEFL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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