Drug Information

Drug General Information
Drug ID
DXA6ZN
Drug Name
1-[4-(8-Chloro-3-ethylamino-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone
Synonyms
CHEMBL137271
Indication Discovery agent Investigative [1587926]
Formula
C28H29ClN4O
Canonical SMILES
CCNc1cnc2C(=C3CCN(CC3)C(=O)Cc4ccncc4)c5ccc(Cl)cc5CCc2c1
InChI
InChI=1S/C28H29ClN4O/c1-2-31-24-17-22-4-3-21-16-23(29)5-6-25(21)27(28(22)32-18-24)20-9-13-33(14-10-20)26(34)15-19-7-11-30-12-8-19/h5-8,11-12,16-18,31H,2-4,9-10,13-15H2,1H3
InChIKey
TXMDQAGJUQGYMZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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