Drug Information

Drug General Information
Drug ID
DXAV0U
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-(1-oxy-pyridin-4-ylmethyl)-piperidine-1-carboxamidine
Synonyms
CHEMBL352022
Indication Discovery agent Investigative [1587926]
Formula
C27H24BrClN6O
Canonical SMILES
[O-][n+]1ccc(C\\N=C(\\NC#N)/N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C27H24BrClN6O/c28-22-13-21-2-1-20-14-23(29)3-4-24(20)25(26(21)31-16-22)19-7-9-34(10-8-19)27(33-17-30)32-15-18-5-11-35(36)12-6-18/h3-6,11-14,16H,1-2,7-10,15H2,(H,32,33)
InChIKey
GIGXNNUVDWTCGJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.