Drug General Information
Drug ID
DXBR7J
Drug Name
(R)Quinoline-3-carboxylic acid [1-dipentylcarbamoyl-2-(5-hydroxy-1H-indol-3-yl)-ethyl]-amide
Synonyms
CHEMBL324022
Indication Discovery agent Investigative [1587926]
Formula
C31H38N4O3
Canonical SMILES
CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccc(O)cc12)NC(=O)c3cnc4ccccc4c3
InChI
InChI=1S/C31H38N4O3/c1-3-5-9-15-35(16-10-6-4-2)31(38)29(18-23-20-33-28-14-13-25(36)19-26(23)28)34-30(37)24-17-22-11-7-8-12-27(22)32-21-24/h7-8,11-14,17,19-21,29,33,36H,3-6,9-10,15-16,18H2,1-2H3,(H,34,37)/t29-/m1/s1
InChIKey
FHSZJVQHKYABCK-GDLZYMKVSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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