Drug Information

Drug General Information
Drug ID
DXD1VM
Drug Name
1-[3-(5-Ethyl-6-methoxy-naphthalen-2-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one
Synonyms
CHEMBL287940
Indication Discovery agent Investigative [1587926]
Formula
C24H31NO2
Canonical SMILES
CCC(=O)C1C2CCC(CC1c3ccc4c(CC)c(OC)ccc4c3)N2C
InChI
InChI=1S/C24H31NO2/c1-5-18-19-10-7-16(13-15(19)8-12-23(18)27-4)20-14-17-9-11-21(25(17)3)24(20)22(26)6-2/h7-8,10,12-13,17,20-21,24H,5-6,9,11,14H2,1-4H3
InChIKey
AEOXYMZMDLKZPQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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