Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXD5U0
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| Drug Name |
9-(3-hydroxypropyl)-6-(3-(pyridin-3-yl)benzylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL524810
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H19N7O
|
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| Canonical SMILES |
OCCCn1cnc2c(NCc3cccc(c3)c4cccnc4)nc(nc12)C#N
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| InChI |
InChI=1S/C21H19N7O/c22-11-18-26-20(19-21(27-18)28(14-25-19)8-3-9-29)24-12-15-4-1-5-16(10-15)17-6-2-7-23-13-17/h1-2,4-7,10,13-14,29H,3,8-9,12H2,(H,24,26,27)
|
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| InChIKey |
CTXFBWQMUWDDIK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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