Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE2GM
|
||||
| Drug Name |
N-((S)-1-((S)-1-(4-methoxyphenylamino)propan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide
|
||||
| Synonyms |
CHEMBL203328
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H33N3O3
|
||||
| Canonical SMILES |
COc1ccc(NC[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)c2cccc(C)c2)cc1
|
||||
| InChI |
InChI=1S/C24H33N3O3/c1-16(2)13-22(27-23(28)19-8-6-7-17(3)14-19)24(29)26-18(4)15-25-20-9-11-21(30-5)12-10-20/h6-12,14,16,18,22,25H,13,15H2,1-5H3,(H,26,29)(H,27,28)/t18-,22-/m0/s1
|
||||
| InChIKey |
AGKAVQUKOATYJW-AVRDEDQJSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.