Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE3EN
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| Drug Name |
{(S)-1-[2-(4-Cyclohexyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester
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| Synonyms |
CHEMBL304669
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H39N3O4
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc2ccc(OC3CCCCC3)cc2
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| InChI |
InChI=1S/C28H39N3O4/c1-21(2)19-26(31-28(33)34-20-22-9-5-3-6-10-22)27(32)30-18-17-29-23-13-15-25(16-14-23)35-24-11-7-4-8-12-24/h3,5-6,9-10,13-16,21,24,26,29H,4,7-8,11-12,17-20H2,1-2H3,(H,30,32)(H,31,33)/t26-/m0/s1
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| InChIKey |
FFHFOZANIUHLFS-SANMLTNESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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