Drug Information

Drug General Information
Drug ID
DXE3KY
Drug Name
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-3-yl-ethanone
Synonyms
SCH-44324; CHEMBL335685
Indication Discovery agent Investigative [1587926]
Formula
C26H24ClN3O
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)Cc4cccnc4)c5ncccc5CCc2c1
InChI
InChI=1S/C26H24ClN3O/c27-22-7-8-23-21(16-22)6-5-20-4-2-12-29-26(20)25(23)19-9-13-30(14-10-19)24(31)15-18-3-1-11-28-17-18/h1-4,7-8,11-12,16-17H,5-6,9-10,13-15H2
InChIKey
IBAHDARYZDKLAE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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