Drug General Information
Drug ID
DXEN5L
Drug Name
{1-[3-(1H-Imidazol-2-yl)-propyl]-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl}-naphthalen-1-yl-methanone
Synonyms
CHEMBL151851
Indication Discovery agent Investigative [1587926]
Formula
C26H26N4O
Canonical SMILES
O=C(N1CCN(CCCc2ncc[nH]2)c3ccccc3C1)c4cccc5ccccc45
InChI
InChI=1S/C26H26N4O/c31-26(23-11-5-9-20-7-1-3-10-22(20)23)30-18-17-29(16-6-13-25-27-14-15-28-25)24-12-4-2-8-21(24)19-30/h1-5,7-12,14-15H,6,13,16-19H2,(H,27,28)
InChIKey
WDJDQOTWRAMHQU-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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