Drug General Information
Drug ID
DXG3TN
Drug Name
Dimethyl-carbamic acid (R)-3-(4-benzoyl-piperidin-1-yl)-3-oxo-2-(3-m-tolyl-ureido)-propyl ester
Synonyms
CHEMBL105303
Indication Discovery agent Investigative [1587926]
Formula
C26H32N4O5
Canonical SMILES
CN(C)C(=O)OC[C@@H](NC(=O)Nc1cccc(C)c1)C(=O)N2CCC(CC2)C(=O)c3ccccc3
InChI
InChI=1S/C26H32N4O5/c1-18-8-7-11-21(16-18)27-25(33)28-22(17-35-26(34)29(2)3)24(32)30-14-12-20(13-15-30)23(31)19-9-5-4-6-10-19/h4-11,16,20,22H,12-15,17H2,1-3H3,(H2,27,28,33)/t22-/m1/s1
InChIKey
QXNYTXXTVJREMH-JOCHJYFZSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.