Drug Information
Drug General Information | |||||
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Drug ID |
DXG8L0
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Drug Name |
6-(4-chlorobenzyl)-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile
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Synonyms |
CHEMBL524045
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C22H23ClN4
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Canonical SMILES |
Clc1ccc(Cc2cc3cnc(nc3n2CCC4CCCCC4)C#N)cc1
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InChI |
InChI=1S/C22H23ClN4/c23-19-8-6-17(7-9-19)12-20-13-18-15-25-21(14-24)26-22(18)27(20)11-10-16-4-2-1-3-5-16/h6-9,13,15-16H,1-5,10-12H2
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InChIKey |
FTEBHYTXXKJNBZ-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
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