Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXGF6M
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| Drug Name |
(S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)-methyl]-2-(3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionamide
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| Synonyms |
CHEMBL335426
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H27N7O4
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| Canonical SMILES |
Cc1cccc(C[C@H](Nc2ccc3COC(=O)c3c2)C(=O)N[C@@H](COCc4cccc(c4)n5cnnn5)C#N)c1
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| InChI |
InChI=1S/C29H27N7O4/c1-19-4-2-5-20(10-19)12-27(32-23-9-8-22-16-40-29(38)26(22)13-23)28(37)33-24(14-30)17-39-15-21-6-3-7-25(11-21)36-18-31-34-35-36/h2-11,13,18,24,27,32H,12,15-17H2,1H3,(H,33,37)/t24-,27+/m1/s1
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| InChIKey |
DREOLTOZTXSMOU-SQHAQQRYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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