Drug Information

Drug General Information
Drug ID
DXGI2K
Drug Name
1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-methyl-piperidin-3-yl)-ethanone
Synonyms
CHEMBL172387
Indication Discovery agent Investigative [1587926]
Formula
C26H32BrClN4O
Canonical SMILES
CN1CCCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)C1
InChI
InChI=1S/C26H32BrClN4O/c1-30-8-2-3-18(17-30)13-24(33)31-9-11-32(12-10-31)26-23-7-6-22(28)15-19(23)4-5-20-14-21(27)16-29-25(20)26/h6-7,14-16,18,26H,2-5,8-13,17H2,1H3
InChIKey
PUHMESLJVPPQNX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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